Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 9/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | BRD2 | P25440 | 1/20 | 0.35 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.35 |
| ▸ | CYBB | P04839 | 2/20 | 0.33 |
| ▸ | NOX5 | Q96PH1 | 2/20 | 0.33 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.33 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.33 |
| ▸ | CDK9 | P50750 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18378608 | 0.84 | BRD4 (0.53) | BRD4CYP3A4CYP2C9BRD2BRD3 | |
| SCHEMBL18318155 | 0.83 | BRD4 (0.38) | BRD4CYP3A4CYP2C9BRD2BRD3 | |
| SCHEMBL16896811 | 0.81 | BRD4 (0.39) | BRD4CYP3A4CYP2C9BRD2BRD3 | |
| SCHEMBL18317400 | 0.79 | SYK (0.39) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL18317139 | 0.78 | BRD4 (0.37) | BRD4CYP3A4CYP2C9BRD2BRD3 | |
| SCHEMBL18377960 | 0.76 | BRD4 (0.47) | BRD4CYP3A4CYP2C9BRD2BRD3 | |
| SCHEMBL18317124 | 0.74 | BRD4 (0.43) | BRD4CYP3A4CYP2C9BRD2BRD3 | |
| SCHEMBL18317130 | 0.74 | BRD4 (0.43) | BRD4CYP3A4CYP2C9BRD2BRD3 | |
| SCHEMBL18317111 | 0.74 | BRD4 (0.44) | BRD4CYP3A4CYP2C9BRD2BRD3 | |
| SCHEMBL18317121 | 0.73 | BRD4 (0.44) | BRD4CYP3A4CYP2C9BRD2BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160368906-A1 | BICYCLIC HETEROCYCLIC DERIVATIVES AS BROMODOMAIN INHIBITORS | ORION CORPORATION (FI) | 2016-12-22 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160368906-A1 | BICYCLIC HETEROCYCLIC DERIVATIVES AS BROMODOMAIN INHIBITORS | BRD1, BRD2, BRD3 | BRD4 4/4885CYP3A4 1942/4885CYP2C9 1528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.