Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 18/20 | 0.37 |
| ▸ | BRD2 | P25440 | 8/20 | 0.37 |
| ▸ | BRD3 | Q15059 | 7/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18317121 | 0.87 | BRD4 (0.44) | BRD4BRD2BRD3CYP3A4CYP2C9 | |
| SCHEMBL18317413 | 0.83 | BRD4 (0.41) | BRD4BRD2BRD3CYP3A4CYP2C9 | |
| SCHEMBL18378608 | 0.83 | BRD4 (0.53) | BRD4BRD2BRD3CYP3A4CYP2C9 | |
| SCHEMBL18317126 | 0.82 | BRD4 (0.41) | BRD4BRD2BRD3CYP1A2CYP3A4 | |
| SCHEMBL18317135 | 0.81 | BRD4 (0.42) | BRD4BRD2BRD3EZH2CYP3A4 | |
| SCHEMBL18317117 | 0.80 | BRD4 (0.43) | BRD4BRD2BRD3CYP1A2EZH2 | |
| SCHEMBL18317200 | 0.79 | BRD4 (0.36) | BRD4BRD2BRD3CYP1A2CYP3A4 | |
| SCHEMBL18377960 | 0.78 | BRD4 (0.47) | BRD4BRD2BRD3CYP3A4CYP2C9 | |
| SCHEMBL18317269 | 0.77 | BRD4 (0.44) | BRD4BRD2BRD3CYP1A2CYP3A4 | |
| SCHEMBL18317113 | 0.77 | BRD4 (0.41) | BRD4BRD2BRD3CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160368906-A1 | BICYCLIC HETEROCYCLIC DERIVATIVES AS BROMODOMAIN INHIBITORS | ORION CORPORATION (FI) | 2016-12-22 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160368906-A1 | BICYCLIC HETEROCYCLIC DERIVATIVES AS BROMODOMAIN INHIBITORS | BRD1, BRD2, BRD3 | BRD4 4/4885BRD2 2/4885BRD3 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.