Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 12/20 | 0.44 |
| ▸ | BRD4 | O60885 | 13/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | BRD2 | P25440 | 1/20 | 0.40 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18317120 | 0.80 | BRD4 (0.43) | CREBBPBRD4CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL18377959 | 0.79 | BRD4 (0.47) | CREBBPBRD4CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL18317134 | 0.79 | BRD4 (0.42) | CREBBPBRD4CYP3A4CYP2C9BRD2 | |
| SCHEMBL18317125 | 0.78 | BRD4 (0.41) | BRD4CYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL18317269 | 0.77 | BRD4 (0.44) | CREBBPBRD4CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL18317412 | 0.77 | BRD4 (0.41) | BRD4CYP3A4CYP2C9BRD2BRD3 | |
| SCHEMBL18378607 | 0.77 | BRD4 (0.53) | CREBBPBRD4CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL18317200 | 0.77 | BRD4 (0.36) | BRD4CYP3A4CYP1A2CYP2C9BRD2 | |
| SCHEMBL18317116 | 0.76 | BRD4 (0.43) | CREBBPBRD4CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL18317112 | 0.75 | BRD4 (0.43) | CREBBPBRD4CYP3A4CYP2C9BRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160368906-A1 | BICYCLIC HETEROCYCLIC DERIVATIVES AS BROMODOMAIN INHIBITORS | ORION CORPORATION (FI) | 2016-12-22 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160368906-A1 | BICYCLIC HETEROCYCLIC DERIVATIVES AS BROMODOMAIN INHIBITORS | BRD1, BRD2, BRD3 | CREBBP 107/4885BRD4 4/4885CYP3A4 1942/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.