Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BUB1 | O43683 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20212640 | 1.00 | BUB1 (1.00) | BUB1 | |
| SCHEMBL21894288 | 0.90 | BUB1 (0.83) | BUB1 | |
| SCHEMBL20212619 | 0.90 | BUB1 (1.00) | BUB1 | |
| SCHEMBL18320313 | 0.90 | BUB1 (0.86) | BUB1 | |
| SCHEMBL20212628 | 0.90 | BUB1 (1.00) | BUB1 | |
| SCHEMBL18321142 | 0.89 | BUB1 (1.00) | BUB1 | |
| SCHEMBL20233892 | 0.88 | BUB1 (1.00) | BUB1 | |
| SCHEMBL18320299 | 0.88 | BUB1 (1.00) | BUB1 | |
| SCHEMBL20212621 | 0.87 | BUB1 (1.00) | BUB1 | |
| SCHEMBL18320238 | 0.87 | BUB1 (1.00) | BUB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3310775-A1 | 3-AMINO-1,5,6,7-TETRAHYDRO-4H-INDOL-4-ONES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-04-25 | — | — | EP | disclosed |
| WO-2016202755-A1 | 3-AMINO-1,5,6,7-TETRAHYDRO-4H-INDOL-4-ONES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-12-22 | — | — | WO | disclosed |