Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18321080 | 0.86 | NAMPT (0.46) | SLC2A1POLBIDO1TDO2MEN1 | |
| SCHEMBL18321098 | 0.85 | KDM4E (0.43) | SLC2A1POLBTSHRHPGDLMNA | |
| SCHEMBL18321067 | 0.83 | JAK2 (0.51) | SLC2A1POLBGRM2TDO2MEN1 | |
| SCHEMBL18321164 | 0.83 | PDE8B (0.51) | SLC2A1GRM2 | |
| SCHEMBL18321167 | 0.81 | GRM2 (0.52) | GRM2KMT2ALMNA | |
| SCHEMBL18321343 | 0.81 | PDE8B (0.53) | POLBMEN1KMT2AMETRXFP1 | |
| Hydrochloric Acid SCHEMBL18321023 | 0.80 | SLC2A1 (0.47) | SLC2A1POLBGRM2IDO1TDO2 | |
| SCHEMBL2368116 | 0.80 | KMT2A (0.42) | POLBIDO1KMT2ATSHRGAA | |
| SCHEMBL18321341 | 0.80 | CYP19A1 (0.48) | TSHR | |
| SCHEMBL18320781 | 0.79 | TP53 (0.47) | TSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016202935-A1 | GLUCOSE TRANSPORT INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-12-22 | — | — | WO | disclosed |