SCHEMBL18321237

SCHEMBL18321237

Cc1nn(Cc2ccc(F)cc2)c(C)c1NC(=O)c1cc(-c2cccc(C(N)=O)c2)nc2ccccc12

nearest known ligand 0.67

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 15/20 0.67
SLC2A3 P11169 14/20 0.61
SLC2A4 P14672 13/20 0.61
SLC2A2 P11168 6/20 0.58
PTGER4 P35408 4/20 0.51
TP53 P04637 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18320705 0.92 SLC2A1 (0.76) SLC2A1SLC2A3SLC2A4SLC2A2PTGER4
SCHEMBL18320982 0.90 SLC2A1 (0.65) SLC2A1SLC2A3SLC2A4SLC2A2PTGER4
SCHEMBL18320819 0.86 SLC2A1 (0.66) SLC2A1SLC2A3SLC2A4SLC2A2TP53
SCHEMBL16855671 0.86 SLC2A1 (0.75) SLC2A1SLC2A3SLC2A4SLC2A2PTGER4
SCHEMBL18320673 0.85 SLC2A1 (0.65) SLC2A1SLC2A3SLC2A4SLC2A2PTGER4
SCHEMBL18320586 0.85 SLC2A1 (0.68) SLC2A1SLC2A3SLC2A4SLC2A2TP53
SCHEMBL18320799 0.84 SLC2A1 (0.72) SLC2A1SLC2A3SLC2A4SLC2A2PTGER4
SCHEMBL18320793 0.84 SLC2A1 (0.84) SLC2A1SLC2A3SLC2A4SLC2A2PTGER4
SCHEMBL16832934 0.84 SLC2A1 (0.81) SLC2A1SLC2A3SLC2A4SLC2A2TP53
SCHEMBL16832385 0.83 SLC2A1 (0.70) SLC2A1SLC2A3SLC2A4SLC2A2PTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016202898-A1 GLUCOSE TRANSPORT INHIBITORS BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2016-12-22 WO claimed