Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 20/20 | 0.86 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18323104 | 0.94 | PTPN11 (0.84) | PTPN11 | |
| SCHEMBL30367288 | 0.93 | PTPN11 (1.00) | PTPN11 | |
| SCHEMBL17669823 | 0.93 | PTPN11 (1.00) | PTPN11 | |
| SCHEMBL17669852 | 0.93 | PTPN11 (1.00) | PTPN11 | |
| SCHEMBL18323102 | 0.92 | PTPN11 (0.85) | PTPN11 | |
| SCHEMBL17669840 | 0.89 | PTPN11 (0.89) | PTPN11 | |
| SCHEMBL18323111 | 0.89 | PTPN11 (0.79) | PTPN11 | |
| SCHEMBL30366686 | 0.89 | PTPN11 (0.85) | PTPN11 | |
| SCHEMBL17669842 | 0.89 | PTPN11 (0.85) | PTPN11 | |
| SCHEMBL17669851 | 0.88 | PTPN11 (1.00) | PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9522881-B2 | Hydroxyindole carboxylic acid based inhibitors for oncogenic Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2) | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2016-12-20 | — | — | US | disclosed |