Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | MITF | O75030 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.32 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| N-Allyl-2-Chloroacetamide SCHEMBL5497997 | 0.78 | — | — | |
| SCHEMBL6454076 | 0.76 | — | — | |
| SCHEMBL14538073 | 0.75 | SMN1; SMN2 (0.36) | SMN1; SMN2TSHRMAPTNPC1RAB9A | |
| SCHEMBL15368032 | 0.74 | — | — | |
| SCHEMBL12675070 | 0.74 | — | — | |
| SCHEMBL21496313 | 0.72 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1TSHRMAPTNPC1 | |
| SCHEMBL10271171 | 0.70 | — | — | |
| Ethylene SCHEMBL27671006 | 0.70 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1TSHRMAPTNPC1 | |
| SCHEMBL18597141 | 0.69 | HPGD (0.33) | ALDH1A1TSHRMAPTKMT2A | |
| SCHEMBL19638574 | 0.67 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1TSHRMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3106458-A1 | MALEATE OF ANTI-PRION COMPOUND, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL COMPOSITION THEREOF | Gifu University (JP) | 2016-12-21 | — | — | EP | disclosed |