SCHEMBL18326009

SCHEMBL18326009

c1ccc(C2(c3ccc(N(c4ccc(-c5ccc6sc7ccccc7c6c5)cc4)c4ccc5ccccc5c4)cc3)c3ccccc3-c3ccccc32)cc1

nearest known ligand 0.32

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
OPRK1 P41145 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
S1PR4 O95977 2/20 0.31
S1PR5 Q9H228 2/20 0.31
PIM3 Q86V86 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17126582 0.97 S1PR5 (0.33) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL18326022 0.96 PIM3 (0.33) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL17126510 0.96 S1PR5 (0.33) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL17806823 0.94
SCHEMBL17126671 0.94 S1PR5 (0.33) S1PR4S1PR5PIM3
SCHEMBL17804800 0.94 KDM4E (0.30) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL16996026 0.94 S1PR4 (0.32) S1PR4S1PR5
SCHEMBL18326045 0.93 PIM3 (0.31) PIM3
SCHEMBL18326084 0.93 S1PR5 (0.33) S1PR4S1PR5
SCHEMBL17805092 0.93 MAPT (0.36) KDM4EMEN1LMNAMAPTOPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11563179-B2 Compound, organic optoelectronic element comprising same and display device thereof SAMSUNG SDI CO., LTD. (KR) 2023-01-24 US disclosed
US-20160372666-A1 COMPOUND, ORGANIC OPTOELECTRONIC ELEMENT COMPRISING SAME AND DISPLAY DEVICE THEREOF SAMSUNG SDI CO., LTD. (KR) 2016-12-22 US disclosed
US-20160372666-A1 COMPOUND, ORGANIC OPTOELECTRONIC ELEMENT COMPRISING SAME AND DISPLAY DEVICE THEREOF SAMSUNG SDI CO., LTD. (KR) 2016-12-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160372666-A1 COMPOUND, ORGANIC OPTOELECTRONIC ELEMENT COMPRISING SAME AND DISPLAY DEVICE THEREOF OR10J3, OR51E2, ORMDL3 KDM4E 2569/4885MEN1 958/4885LMNA 4464/4885
US-11563179-B2 Compound, organic optoelectronic element comprising same and display device thereof OR10J3, OR51E2, ORMDL3 KDM4E 2569/4885MEN1 958/4885LMNA 4464/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.