Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.95 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.95 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.62 |
| ▸ | NOD1 | Q9Y239 | 6/20 | 0.44 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 2/20 | 0.43 |
| ▸ | FNTB | P49356 | 2/20 | 0.43 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.42 |
| ▸ | GRM8 | O00222 | 1/20 | 0.41 |
| ▸ | GRM6 | O15303 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glutathione SCHEMBL14125840 | 1.00 | PTGS1 (0.95) | PTGS1GSTK1GLO1NOD1SLC7A11 | |
| Glutathione SCHEMBL2124417 | 1.00 | PTGS1 (0.95) | PTGS1GSTK1GLO1NOD1SLC7A11 | |
| Glutathione SCHEMBL22115882 | 1.00 | PTGS1 (0.95) | PTGS1GSTK1GLO1NOD1SLC7A11 | |
| Glutathione SCHEMBL14125841 | 1.00 | PTGS1 (0.95) | PTGS1GSTK1GLO1NOD1SLC7A11 | |
| Glutathione SCHEMBL2124421 | 1.00 | PTGS1 (0.95) | PTGS1GSTK1GLO1NOD1SLC7A11 | |
| Glutathione SCHEMBL183280 | 1.00 | PTGS1 (0.95) | PTGS1GSTK1GLO1NOD1SLC7A11 | |
| Glutathione SCHEMBL183279 | 1.00 | PTGS1 (0.95) | PTGS1GSTK1GLO1NOD1SLC7A11 | |
| Glutathione SCHEMBL20542219 | 0.99 | PTGS1 (0.92) | PTGS1GSTK1GLO1NOD1SLC7A11 | |
| Glutathione SCHEMBL20542215 | 0.99 | PTGS1 (0.92) | PTGS1GSTK1GLO1NOD1SLC7A11 | |
| Glutathione SCHEMBL13105609 | 0.97 | PTGS1 (1.00) | PTGS1GSTK1GLO1NOD1FNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220082564-A1 | MARKER FOR ASSESSING SENSITIVITY TO COMBINATION ANTICANCER DRUG | KEIO UNIVERSITY (JP) | 2022-03-17 | — | — | US | claimed |
| EP-3650852-B1 | BLOOD BASED BIOMARKERS FOR DIAGNOSING ATHEROSCLEROTIC CORONARY ARTERY DISEASE | GLOBAL GENOMICS GROUP LLC (US) | 2021-08-18 | — | — | EP | claimed |
| CN-108508168-B | Combined sensitivity-determining marker for anticancer agent | 学校法人庆应义塾 | 2021-08-17 | — | — | CN | claimed |
| EP-3858344-A1 | MARKER FOR ASSESSING SENSITIVITY TO COMBINATION ANTICANCER DRUG | Keio University (JP) | 2021-08-04 | — | — | EP | claimed |
| EP-3326632-B1 | COMBINED ANTICANCER DRUG SENSITIVITY-DETERMINING MARKER | UNIV KEIO (JP) | 2021-04-07 | — | — | EP | claimed |
| EP-3779451-A1 | MARKER FOR DETERMINING SENSITIVITY OF IRINOTECAN-CONTAINING ANTI-CANCER AGENT THERAPY | Keio University (JP) | 2021-02-17 | — | — | EP | claimed |
| EP-3575799-B1 | MARKER FOR DETERMINATION OF SENSITIVITY TO ANTICANCER AGENT | UNIV KEIO (JP) | 2020-06-24 | — | — | EP | claimed |
| CN-107252428-B | Marker for determination of sensitivity to anticancer agent | 学校法人庆应义塾 | 2020-04-14 | — | — | CN | claimed |
| WO-2020067228-A1 | MARKER FOR ASSESSING SENSITIVITY TO COMBINATION ANTICANCER DRUG | 学校法人慶應義塾 | 2020-04-02 | — | — | WO | claimed |
| EP-3575799-A1 | MARKER FOR DETERMINATION OF SENSITIVITY TO ANTICANCER AGENT | Keio University (JP) | 2019-12-04 | — | — | EP | claimed |
| US-20170299597-A1 | COMBINED ANTICANCER DRUG SENSITIVITY-DETERMINING MARKER | KEIO UNIVERSITY (JP) | 2017-10-19 | — | — | US | claimed |
| CN-107252428-A | The marker for determination of sensitivity to anti-cancer agent | 学校法人庆应义塾 | 2017-10-17 | — | — | CN | claimed |
| CN-106537145-A | Small molecule biochemical profiling of individual subjects for disease diagnosis and health assessment | 麦特博隆股份有限公司 | 2017-03-22 | — | — | CN | claimed |
| EP-3139172-A2 | MARKER FOR DETERMINATION OF SENSITIVITY TO ANTICANCER AGENT | Keio University (JP) | 2017-03-08 | — | — | EP | claimed |
| CN-105744946-A | Modification and Novel Compositions of Human Secretoglobin Proteins | 希拉布朗治疗有限公司 | 2016-07-06 | — | — | CN | claimed |
| US-20150038522-A1 | COMBINED ANTICANCER DRUG SENSITIVITY-DETERMINING MARKER | KEIO UNIVERSITY (JP) | 2015-02-05 | — | — | US | claimed |
| EP-2818870-A1 | COMBINED ANTICANCER DRUG SENSITIVITY-DETERMINING MARKER | Keio University (JP) | 2014-12-31 | — | — | EP | claimed |
| EP-2690442-A1 | MARKER FOR DETERMINATION OF SENSITIVITY TO ANTICANCER AGENT | Keio University (JP) | 2014-01-29 | — | — | EP | claimed |
| EP-2629769-A1 | CYSTEINE AND FOOD INTAKE | Nestec S.A. (CH) | 2013-08-28 | — | — | EP | claimed |
| WO-2012052463-A1 | CYSTEINE AND FOOD INTAKE | NESTEC S.A. (CH) | 2012-04-26 | — | — | WO | claimed |