Benzoic Acid

Benzoic Acid

SCHEMBL1833087

CC(N)O.O=C(O)c1ccccc1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D

The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.67
DAO P14920 1/20 0.67
NAPRT Q6XQN6 1/20 0.67
CES2 O00748 3/20 0.56
CES1 P23141 3/20 0.56
SRD5A2 P31213 1/20 0.56
TP53 P04637 1/20 0.50
MAPT P10636 2/20 0.48
POLB P06746 1/20 0.48
CYP3A4 P08684 1/20 0.48
PARP1 P09874 1/20 0.48
CYP2C19 P33261 1/20 0.48
RECQL P46063 1/20 0.48
BLM P54132 1/20 0.48
PMP22 Q01453 1/20 0.48
HSD17B10 Q99714 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
LMNA P02545 3/20 0.47
SMN1; SMN2 Q16637 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoic Acid SCHEMBL1899964 0.93 TSHR (0.70) TSHRDAONAPRTCES2CES1
Benzoic Acid SCHEMBL5607281 0.90 TSHR (0.74) TSHRDAONAPRTCES2CES1
Benzoic Acid SCHEMBL1913806 0.90 TSHR (0.74) TSHRDAONAPRTCES2CES1
Benzoic Acid SCHEMBL7865148 0.90 TSHR (0.74) TSHRDAONAPRTCES2CES1
Benzoic Acid SCHEMBL15658034 0.88 TSHR (0.64) TSHRDAONAPRTCES2CES1
Benzoic Acid SCHEMBL28648667 0.88 TSHR (0.70) TSHRDAONAPRTCES2CES1
Benzoic Acid SCHEMBL5082990 0.88 TSHR (0.70) TSHRDAONAPRTCES2CES1
Benzoic Acid SCHEMBL28327607 0.87 TSHR (0.78) TSHRDAONAPRTCES2CES1
Benzoic Acid SCHEMBL25228351 0.86 TSHR (0.67) TSHRDAONAPRTCES2CES1
Benzoic Acid SCHEMBL7436169 0.86 TSHR (0.67) TSHRDAONAPRTCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10815421-B2 Flow back aids ETHOX CHEMICALS, LLC (US) 2020-10-27 US claimed
US-20150047849-A1 FLOW BACK AIDS FIRST NATIONAL BANK OF PENNSYLVANIA 2015-02-19 US claimed
US-8800224-B1 Corrosion inhibiting vapor for use in connection with encased articles CORTEC CORPORATION (US) 2014-08-12 US claimed
EP-1954879-A2 AN ANTICORROSIVE PAPER OR PAPERBOARD MATERIAL INTERNATIONAL PAPER COMPANY (US) 2008-08-13 EP claimed
US-7264707-B1 Applying a mixture that includes cyclohexylammonium benzoate; monoethanolammonium benzoate; dicyclohexylammonium nitrate; and up to 5 % by weight fumed silica, and may further include tolyltriazole; sacrificial anode CORTEC CORPORATION (US) 2007-09-04 US claimed
WO-2007053597-A2 AN ANTICORROSIVE PAPER OR PAPERBOARD MATERIAL INTERNATIONAL PAPER COMPANY (US) 2007-05-10 WO claimed
US-20070098932-A1 Anticorrosive paper or paperboard material INTERNATIONAL PAPER COMPANY 2007-05-03 US claimed
US-9435037-B2 Method for treating elongate metal tension member with volatile corrosion inhibitors CORTEC CORPORATION (US) 2016-09-06 US disclosed
US-9328220-B2 Liquids INNOVIA FILMS LIMITED (GB) 2016-05-03 US disclosed
US-8992798-B2 Liquids INNOVIA FILMS LIMITED (GB) 2015-03-31 US disclosed
US-8800224-B1 Corrosion inhibiting vapor for use in connection with encased articles CORTEC CORPORATION (US) 2014-08-12 US disclosed
US-20140205496-A1 Corrosion Inhibiting Vapor for Use in Connection with Encased Articles CORTEC CORPORATION (US) 2014-07-24 US disclosed
US-8784686-B2 Liquids INNOVIA FILMS LIMITED (GB) 2014-07-22 US disclosed
US-6420470-B1 PLASTIC RESIN FILM WITH PROTECTIVE ENCLOSURES CORTEC CORPORATION 2002-07-16 US disclosed
EP-1116746-A2 Biodegradable film CORTEC CORPORATION (US) 2001-07-18 EP disclosed
US-6156929-A Biodegradable film CORTEC CORPORATION (US) 2000-12-05 US disclosed
US-6085905-A Water-soluble containers for water cooling towers and boilers CORTEC CORPORATION (US) 2000-07-11 US disclosed
EP-0990676-A1 Biodegradable vapor corrosion inhibitor products CORTEC CORPORATION (US) 2000-04-05 EP disclosed
US-6028160-A A BLENDS CONSISTING OF POLYETHYLENE, STARCH, POLYLACTIC ACID OR POLYCAPROLACTONE, AND A POLYESTER COPOLYMER OF BUTANEDIOL, ADIPIC ACID, SUCCINIC ACID, AND TEREPHTHALIC ACID; BULK FILLER PACKING FORMS FOR PACKAGING APPLICATIONS CORTEC CORPORATION (US) 2000-02-22 US disclosed
US-4735358-A Method and apparatus of vaporizing active substances DAIKEN IKO KABUSHIKI KAISHA (JP) 1988-04-05 US disclosed