Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL11628461 | 0.85 | HTT (0.42) | ALDH1A1TSHRHTTCES2CES1 | |
| Ethylene Glycol SCHEMBL29212815 | 0.85 | DPP4 (0.37) | ALDH1A1TSHRHTTCES2CES1 | |
| SCHEMBL205832 | 0.82 | HTT (0.45) | ALDH1A1TSHRHTTCES2CES1 | |
| SCHEMBL5406015 | 0.79 | HTT (0.43) | ALDH1A1TSHRHTTCES2CES1 | |
| SCHEMBL6227879 | 0.79 | HTT (0.43) | ALDH1A1TSHRHTTCES2CES1 | |
| SCHEMBL1303087 | 0.79 | HTT (0.43) | ALDH1A1TSHRHTTCES2CES1 | |
| SCHEMBL6903601 | 0.79 | HTT (0.48) | ALDH1A1TSHRHTTCES2CES1 | |
| SCHEMBL1157937 | 0.79 | HTT (0.43) | ALDH1A1TSHRHTTCES2CES1 | |
| SCHEMBL4899263 | 0.79 | DPP4 (0.43) | ALDH1A1TSHRHTTCES2CES1 | |
| SCHEMBL70425 | 0.79 | DPP4 (0.43) | ALDH1A1TSHRHTTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9328220-B2 | Liquids | INNOVIA FILMS LIMITED (GB) | 2016-05-03 | — | — | US | disclosed |
| US-8992798-B2 | Liquids | INNOVIA FILMS LIMITED (GB) | 2015-03-31 | — | — | US | disclosed |
| US-8784686-B2 | Liquids | INNOVIA FILMS LIMITED (GB) | 2014-07-22 | — | — | US | disclosed |
| US-20140187684-A1 | LIQUIDS | INNOVIA FILMS LIMITED (GB) | 2014-07-03 | — | — | US | disclosed |
| US-20110257433-A1 | LIQUIDS | THE UNIVERSITY OF YORK (GB) | 2011-10-20 | — | — | US | disclosed |
| EP-2322497-A1 | Ionic liquids comprising nitrogen containing cations | Innovia Films Limited (GB) | 2011-05-18 | — | — | EP | disclosed |
| US-20070185330-A1 | Liquids | THE UNIVERSITY OF YORK (GB) | 2007-08-09 | — | — | US | disclosed |