Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16752919 | 0.91 | ALK (1.00) | ALK | |
| SCHEMBL16753002 | 0.91 | ALK (1.00) | ALK | |
| SCHEMBL16772120 | 0.90 | ALK (1.00) | ALK | |
| SCHEMBL16752963 | 0.89 | ALK (0.92) | ALK | |
| SCHEMBL16772119 | 0.88 | ALK (1.00) | ALK | |
| SCHEMBL16772178 | 0.87 | ALK (1.00) | ALK | |
| SCHEMBL18334848 | 0.87 | ALK (0.93) | ALK | |
| SCHEMBL18334852 | 0.87 | ALK (0.93) | ALK | |
| SCHEMBL16772158 | 0.87 | ALK (1.00) | ALK | |
| SCHEMBL16752977 | 0.86 | ALK (1.00) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2883875-B1 | N2,N4-BIS(4-(PIPERAZINE-1-YL)PHENYL)PIRIMIDINE-2,4-DIAMINE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND COMPOSITION CONTAINING THE SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING CANCER | KOREA RES INST CHEMICAL TECH (KR) | 2016-12-28 | — | — | EP | claimed |