Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL167656 | 0.91 | — | — | |
| SCHEMBL29094055 | 0.86 | — | — | |
| Ammonia Solution, Strong SCHEMBL11128762 | 0.86 | — | — | |
| SCHEMBL27555550 | 0.86 | — | — | |
| SCHEMBL28239834 | 0.86 | — | — | |
| SCHEMBL29217515 | 0.86 | — | — | |
| SCHEMBL28942165 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL28285577 | 0.86 | — | — | |
| Ethane SCHEMBL11524507 | 0.82 | — | — | |
| Urea SCHEMBL29089000 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670176-B2 | Process for the preparation of zileuton | STRIDES SHASUN LIMITED (IN) | 2017-06-06 | — | — | US | claimed |
| US-20160376251-A1 | Process for the Preparation of Zileuton | STRIDES SHASUN LIMITED (IN) | 2016-12-29 | — | — | US | claimed |
| US-9670176-B2 | Process for the preparation of zileuton | STRIDES SHASUN LIMITED (IN) | 2017-06-06 | — | — | US | disclosed |
| US-20160376251-A1 | Process for the Preparation of Zileuton | STRIDES SHASUN LIMITED (IN) | 2016-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160376251-A1 | Process for the Preparation of Zileuton | CYP2B6, UGT1A6, CYP2A6 | HDAC6 589/4885HDAC8 2151/4885HDAC2 687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.