⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22710953 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL22263983 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL22263984 | 0.97 | — | — | |
| Bicarbonate SCHEMBL17224665 | 0.89 | OR51E2 (0.38) | — | |
| Phosphoric Acid SCHEMBL6295624 | 0.87 | ANPEP (0.33) | — | |
| Acetic Acid SCHEMBL1098684 | 0.84 | OR51E2 (0.35) | — | |
| Water SCHEMBL2424971 | 0.75 | — | — | |
| SCHEMBL6326055 | 0.75 | — | — | |
| SCHEMBL2403021 | 0.72 | — | — | |
| SCHEMBL13925424 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0844233-B1 | Process for preparing alpha-amino acid amides, alpha-amino acids and derivatives thereof | DSM NV (NL) | 2002-04-03 | — | — | EP | claimed |
| US-5977406-A | Process for preparing α-amino acid amides, α-amino acids and derivatives thereof | DSM NV (NL) | 1999-11-02 | — | — | US | claimed |
| EP-0844233-A1 | Process for preparing alpha-amino acid amides, alpha-amino acids and derivatives thereof | DSM N.V. (NL) | 1998-05-27 | — | — | EP | claimed |
| US-5030750-A | Process for preparing DL-serine and process for separation and purification of the same | RESEARCH ASSOCIATION FOR UTILIZATION OF LIGHT OIL (JP) | 1991-07-09 | — | — | US | claimed |
| JP-10182574-A | — | — | None | — | — | JP | disclosed |
| US-12116343-B2 | Inhibitors of APOL1 and methods of using same | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2024-10-15 | — | — | US | disclosed |
| US-11795164-B2 | 2-heteroaryl-3-oxo-2,3-dihydropyridazine-4-carboxamides for the treatment of cancer | BAYER AKTIENGESELLSCHAFT (DE) | 2023-10-24 | — | — | US | disclosed |
| US-20230121195-A1 | 2-HETEROARYL-3-OXO-2,3-DIHYDROPYRIDAZINE-4-CARBOXAMIDES FOR THE TREATMENT OF CANCER | BAYER AKTIENGESELLSCHAFT (DE) | 2023-04-20 | — | — | US | disclosed |
| US-20220340523-A1 | INHIBITORS OF APOL1 AND METHODS OF USING SAME | VERTEX PHARMACEUTICALS INCORPORATED | 2022-10-27 | — | — | US | disclosed |
| EP-3580211-B1 | 2-HETEROARYL-3-OXO-2,3-DIHYDROPYRIDAZINE-4-CARBOXAMIDES FOR THE TREATMENT OF CANCER | BAYER AG (DE) | 2020-12-02 | — | — | EP | disclosed |
| CN-108003077-B | Preparation and purification method of amino acid compound | 河北威远生物化工有限公司 | 2020-03-31 | — | — | CN | disclosed |
| CN-108003077-A | A kind of preparation of amino-acid compound and purification process | 河北威远生物化工有限公司 | 2018-05-08 | — | — | CN | disclosed |
| EP-0844233-A1 | Process for preparing alpha-amino acid amides, alpha-amino acids and derivatives thereof | DSM N.V. (NL) | 1998-05-27 | — | — | EP | disclosed |
| EP-0844233-A1 | Process for preparing alpha-amino acid amides, alpha-amino acids and derivatives thereof | DSM N.V. (NL) | 1998-05-27 | — | — | EP | disclosed |
| US-5587303-A | HYDROLYSIS OF NITRILE CONTAINING AMINE COMPOUND | NIPPON MINING COMPANY, LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| EP-0332379-B1 | Production process of L-alpha-amino acids | JAPAN ENERGY CORP (JP) | 1996-08-14 | — | — | EP | disclosed |
| EP-0376184-B1 | Process for preparing DL-serine and process for separation and purification of the same | LIGHT OIL UTILIZATION RES ASS (JP) | 1995-03-15 | — | — | EP | disclosed |
| US-5030750-A | Process for preparing DL-serine and process for separation and purification of the same | RESEARCH ASSOCIATION FOR UTILIZATION OF LIGHT OIL (JP) | 1991-07-09 | — | — | US | disclosed |
| EP-0376184-A2 | Process for preparing DL-serine and process for separation and purification of the same | MITSUBISHI CHEMICAL CORPORATION (JP) | 1990-07-04 | — | — | EP | disclosed |
| EP-0332379-A2 | Production process of L-alpha-amino acids | JAPAN ENERGY CORPORATION (JP) | 1989-09-13 | — | — | EP | disclosed |