Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 19/20 | 0.42 |
| ▸ | KLK1 | P06870 | 2/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1834114 | 1.00 | KLKB1 (0.42) | KLKB1KLK1GRM2 | |
| SCHEMBL1833676 | 0.82 | KLKB1 (0.49) | KLKB1KLK1GRM2 | |
| SCHEMBL1833142 | 0.79 | GRM2 (0.57) | KLKB1KLK1GRM2 | |
| SCHEMBL2161468 | 0.78 | KLKB1 (0.52) | KLKB1KLK1 | |
| SCHEMBL1843900 | 0.78 | KLKB1 (0.54) | KLKB1KLK1 | |
| SCHEMBL2161062 | 0.77 | KLKB1 (0.51) | KLKB1KLK1 | |
| SCHEMBL2161366 | 0.77 | KLKB1 (0.40) | KLKB1KLK1GRM2 | |
| SCHEMBL2162121 | 0.76 | KLKB1 (0.56) | KLKB1KLK1 | |
| SCHEMBL13616210 | 0.76 | KLKB1 (0.41) | KLKB1KLK1 | |
| SCHEMBL2161475 | 0.76 | KLKB1 (0.39) | KLKB1KLK1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110184188-A1 | Insecticidal Benzenedicarboxamide Derivative | BAYER CROPSCIENCE AG (DE) | 2011-07-28 | — | — | US | disclosed |
| EP-2318374-A2 | INSECTICIDAL BENZENEDICARBOXAMIDE DERIVATIVE | Bayer CropScience AG (DE) | 2011-05-11 | — | — | EP | disclosed |
| WO-2010012442-A2 | INSECTICIDAL BENZENEDICARBOXAMIDE DERIVATIVE | BAYER CROPSCIENCE AG (DE) | 2010-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110184188-A1 | Insecticidal Benzenedicarboxamide Derivative | DDT, BRD9, BCL2A1 | KLKB1 4858/4885KLK1 4844/4885GRM2 3280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.