Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 20/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18345144 | 1.00 | TNK2 (0.82) | TNK2 | |
| SCHEMBL4357925 | 0.90 | TNK2 (1.00) | TNK2 | |
| SCHEMBL21044853 | 0.87 | TNK2 (0.82) | TNK2 | |
| SCHEMBL410102 | 0.87 | TNK2 (0.82) | TNK2 | |
| SCHEMBL13618363 | 0.82 | TNK2 (0.83) | TNK2 | |
| SCHEMBL1131228 | 0.82 | TNK2 (1.00) | TNK2 | |
| SCHEMBL4356082 | 0.80 | TNK2 (1.00) | TNK2 | |
| SCHEMBL4361306 | 0.80 | TNK2 (1.00) | TNK2 | |
| SCHEMBL4358422 | 0.80 | TNK2 (1.00) | TNK2 | |
| SCHEMBL4361594 | 0.79 | TNK2 (1.00) | TNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3313839-A1 | TYROSINE KINASE INHIBITORS | Principia Biopharma Inc. (US) | 2018-05-02 | — | — | EP | disclosed |
| WO-2016210165-A1 | TYROSINE KINASE INHIBITORS | PRINCIPIA BIOPHARMA INC. (US) | 2016-12-29 | — | — | WO | disclosed |