Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 16/20 | 0.53 |
| ▸ | LDHB | P07195 | 1/20 | 0.45 |
| ▸ | F11 | P03951 | 1/20 | 0.43 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.42 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1929826 | 1.00 | GCK (0.53) | GCKLDHBF11CACNA1GCACNA1I | |
| SCHEMBL1931581 | 0.89 | GCK (0.53) | GCKLDHBCACNA1GCACNA1I | |
| SCHEMBL1931585 | 0.89 | GCK (0.53) | GCKLDHBCACNA1GCACNA1I | |
| SCHEMBL1931067 | 0.88 | GCK (0.57) | GCK | |
| SCHEMBL1931068 | 0.88 | GCK (0.57) | GCK | |
| SCHEMBL1931382 | 0.86 | GCK (0.55) | GCK | |
| SCHEMBL1931385 | 0.86 | GCK (0.55) | GCK | |
| SCHEMBL1931004 | 0.84 | GCK (0.69) | GCK | |
| SCHEMBL1931007 | 0.84 | GCK (0.69) | GCK | |
| SCHEMBL1827485 | 0.79 | GCK (0.65) | GCKF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110130365-A1 | Fluorinated Heteroaryls | BENBOW JOHN W | 2011-06-02 | — | — | US | disclosed |
| US-20110130365-A1 | Fluorinated Heteroaryls | BENBOW JOHN W | 2011-06-02 | — | — | US | disclosed |
| EP-2318370-A1 | FLUORINATED HETEROARYLS | Pfizer Inc. (US) | 2011-05-11 | — | — | EP | disclosed |
| WO-2010013161-A1 | FLUORINATED HETEROARYLS | PFIZER INC. (US) | 2010-02-04 | — | — | WO | disclosed |
| WO-2010013161-A1 | FLUORINATED HETEROARYLS | PFIZER INC. (US) | 2010-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110130365-A1 | Fluorinated Heteroaryls | GCKR, GALK1, GCK | GCK 3/4885LDHB 2921/4885F11 640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.