Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL574560 | 0.88 | TAAR1 (0.59) | TAAR1 | |
| SCHEMBL1834781 | 0.80 | TAAR1 (0.70) | TAAR1 | |
| SCHEMBL1834787 | 0.80 | TAAR1 (0.70) | TAAR1 | |
| SCHEMBL1831897 | 0.74 | TAAR1 (0.67) | TAAR1 | |
| SCHEMBL1831899 | 0.74 | TAAR1 (0.67) | TAAR1 | |
| SCHEMBL1833663 | 0.72 | TAAR1 (1.00) | TAAR1 | |
| SCHEMBL1833658 | 0.72 | TAAR1 (1.00) | TAAR1 | |
| SCHEMBL1834773 | 0.71 | — | — | |
| SCHEMBL1962164 | 0.71 | — | — | |
| SCHEMBL1726234 | 0.71 | TAAR1 (0.57) | TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2321287-A1 | 4,5-DIHYDRO-OXAZOL-2-YL DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2011-05-18 | — | — | EP | disclosed |
| WO-2010010014-A1 | 4,5-DIHYDRO-OXAZOL-2-YL DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2010-01-28 | — | — | WO | disclosed |