SCHEMBL18348908

SCHEMBL18348908

CCCOCCSC(C)C

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.41
TDP1 Q9NUW8 1/20 0.34
CCR7 P32248 1/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20127141 0.87 NPC1 (0.32) NPC1RAB9A
SCHEMBL15382348 0.86 TSHR (0.44) HSD17B10NPC1RAB9A
SCHEMBL13509110 0.78 TSHR (0.48)
SCHEMBL14524136 0.78
SCHEMBL23259195 0.76
SCHEMBL13154051 0.76
SCHEMBL12572443 0.76 HSD17B10 (0.31) HSD17B10NPC1RAB9A
SCHEMBL15613622 0.75
SCHEMBL12297337 0.75 HSD17B10 (0.31) HSD17B10NPC1RAB9A
SCHEMBL25495228 0.75 HRH3 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9811011-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2017-11-07 US disclosed
US-20160378001-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2016-12-29 US disclosed