Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Phenylacetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.74 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | PAM | P19021 | 2/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylacetic Acid SCHEMBL27486045 | 0.89 | AKR1B1 (0.85) | AKR1B1ABCC4LMNAGAATSHR | |
| Phenylacetic Acid SCHEMBL10608383 | 0.87 | AKR1B1 (0.74) | AKR1B1ABCC4LMNAGAATSHR | |
| Phenylacetic Acid SCHEMBL28668840 | 0.86 | AKR1B1 (0.81) | AKR1B1ABCC4LMNAGAATSHR | |
| Phenylacetic Acid SCHEMBL7322793 | 0.86 | AKR1B1 (0.90) | AKR1B1ABCC4LMNAGAATSHR | |
| Phenylacetic Acid SCHEMBL27758886 | 0.86 | AKR1B1 (1.00) | AKR1B1ABCC4LMNAGAATSHR | |
| Phenylacetic Acid SCHEMBL28242469 | 0.86 | AKR1B1 (1.00) | AKR1B1ABCC4LMNAGAATSHR | |
| Phenylacetic Acid SCHEMBL1330777 | 0.86 | AKR1B1 (1.00) | AKR1B1ABCC4LMNAGAATSHR | |
| Phenylacetic Acid SCHEMBL9449909 | 0.86 | AKR1B1 (1.00) | AKR1B1ABCC4LMNAGAATSHR | |
| Phenylacetic Acid SCHEMBL13618842 | 0.86 | AKR1B1 (1.00) | AKR1B1ABCC4LMNAGAATSHR | |
| Phenylacetic Acid SCHEMBL1459 | 0.86 | AKR1B1 (1.00) | AKR1B1ABCC4LMNAGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112338091-B | Punch forming process of aluminum alloy radiating fin | 太仓巧洲五金科技有限公司 | 2022-08-02 | — | — | CN | claimed |
| CN-109180054-B | Method for preparing gel reducing agent by sulfonated saccharide compounds | 湖北工业大学 | 2021-06-18 | — | — | CN | claimed |
| CN-109133710-B | Preparation method of naphthalene water reducer matching glue reducer | 湖北工业大学 | 2021-06-18 | — | — | CN | claimed |
| CN-112851193-A | Amphiphilic calcite type calcium carbonate-based gel reducing agent and preparation method thereof | 深圳市天祥新材料有限公司 | 2021-05-28 | — | — | CN | claimed |
| CN-109437643-B | Method for preparing gel reducing agent from amphoteric polyester polycarboxylic acid compound | 湖北工业大学 | 2021-03-02 | — | — | CN | claimed |
| CN-109399990-B | Preparation method of gel reducing agent for matching polycarboxylate superplasticizer | 湖北工业大学 | 2021-03-02 | — | — | CN | claimed |
| CN-112338091-A | Punch forming process of aluminum alloy radiating fin | 太仓巧洲五金科技有限公司 | 2021-02-09 | — | — | CN | claimed |
| CN-109384881-B | Method for preparing gel reducing agent from cationic polymer | 湖北工业大学 | 2020-12-29 | — | — | CN | claimed |
| CN-112338091-B | Punch forming process of aluminum alloy radiating fin | 太仓巧洲五金科技有限公司 | 2022-08-02 | — | — | CN | disclosed |
| CN-109180054-B | Method for preparing gel reducing agent by sulfonated saccharide compounds | 湖北工业大学 | 2021-06-18 | — | — | CN | disclosed |
| CN-109133710-B | Preparation method of naphthalene water reducer matching glue reducer | 湖北工业大学 | 2021-06-18 | — | — | CN | disclosed |
| CN-112851193-A | Amphiphilic calcite type calcium carbonate-based gel reducing agent and preparation method thereof | 深圳市天祥新材料有限公司 | 2021-05-28 | — | — | CN | disclosed |
| CN-109399990-B | Preparation method of gel reducing agent for matching polycarboxylate superplasticizer | 湖北工业大学 | 2021-03-02 | — | — | CN | disclosed |
| CN-109437643-B | Method for preparing gel reducing agent from amphoteric polyester polycarboxylic acid compound | 湖北工业大学 | 2021-03-02 | — | — | CN | disclosed |
| US-8992798-B2 | Liquids | INNOVIA FILMS LIMITED (GB) | 2015-03-31 | — | — | US | disclosed |
| US-8784686-B2 | Liquids | INNOVIA FILMS LIMITED (GB) | 2014-07-22 | — | — | US | disclosed |
| US-20140187684-A1 | LIQUIDS | INNOVIA FILMS LIMITED (GB) | 2014-07-03 | — | — | US | disclosed |
| US-20110257433-A1 | LIQUIDS | THE UNIVERSITY OF YORK (GB) | 2011-10-20 | — | — | US | disclosed |
| EP-2322497-A1 | Ionic liquids comprising nitrogen containing cations | Innovia Films Limited (GB) | 2011-05-18 | — | — | EP | disclosed |
| US-20070185330-A1 | Liquids | THE UNIVERSITY OF YORK (GB) | 2007-08-09 | — | — | US | disclosed |