⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18358906 | 1.00 | — | — | |
| SCHEMBL15428316 | 0.74 | — | — | |
| SCHEMBL1442110 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL16763349 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL15416761 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL15416762 | 0.72 | — | — | |
| SCHEMBL31641981 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL21439826 | 0.70 | — | — | |
| SCHEMBL28883327 | 0.67 | — | — | |
| SCHEMBL21532974 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220024920-A1 | ADO-RESISTANT CYSTEAMINE ANALOGS AND USES THEREOF | HORIZON ORPHAN LLC (US) | 2022-01-27 | — | — | US | disclosed |
| US-10906904-B2 | ADO-resistant cysteamine analogs and uses thereof | HORIZON ORPHAN LLC (US) | 2021-02-02 | — | — | US | disclosed |
| WO-2017004485-A1 | ADO-RESISTANT CYSTEAMINE ANALOGS AND USES THEREOF | RAPTOR PHARMACEUTICALS INC. (US) | 2017-01-05 | — | — | WO | disclosed |