⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18358922 | 0.77 | — | — | |
| SCHEMBL18358896 | 0.77 | — | — | |
| SCHEMBL18358897 | 0.77 | — | — | |
| SCHEMBL27993609 | 0.75 | — | — | |
| SCHEMBL2010663 | 0.73 | — | — | |
| SCHEMBL29414201 | 0.73 | — | — | |
| SCHEMBL13326775 | 0.73 | — | — | |
| SCHEMBL18358866 | 0.73 | — | — | |
| SCHEMBL18358837 | 0.73 | — | — | |
| SCHEMBL1645033 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125737-A1 | HETEROCYCLIC COMPOUNDS AND USE THEREOF | SILEXON AI TECHNOLOGY CO., LTD. (CN) | 2023-07-06 | — | — | WO | disclosed |
| US-20230115413-A1 | Use of Thiol Compounds to Treat Neurological Disease | ZANKEL, TODD C, MR | 2023-04-13 | — | — | US | disclosed |
| US-20220024920-A1 | ADO-RESISTANT CYSTEAMINE ANALOGS AND USES THEREOF | HORIZON ORPHAN LLC (US) | 2022-01-27 | — | — | US | disclosed |
| US-20210069129-A1 | Use of Thiol Compounds to Treat Neurological Disease | ZANKEL, TODD C, MR | 2021-03-11 | — | — | US | disclosed |
| US-10906904-B2 | ADO-resistant cysteamine analogs and uses thereof | HORIZON ORPHAN LLC (US) | 2021-02-02 | — | — | US | disclosed |
| EP-3316877-B1 | ADO-RESISTANT CYSTEAMINE ANALOGS AND USES THEREOF | HORIZON ORPHAN LLC (US) | 2019-10-30 | — | — | EP | disclosed |
| EP-3159341-B1 | PYRIDINO[1,2-A]PYRIMIDONE ANALOGUE USED AS PI3K INHIBITOR | CHAI TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) | 2019-08-21 | — | — | EP | disclosed |
| US-20190029977-A1 | Use of Thiol Compounds to Treat Neurological Disease | ZANKEL, TODD C, MR | 2019-01-31 | — | — | US | disclosed |
| WO-2017004485-A1 | ADO-RESISTANT CYSTEAMINE ANALOGS AND USES THEREOF | RAPTOR PHARMACEUTICALS INC. (US) | 2017-01-05 | — | — | WO | disclosed |