Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1830312 | 1.00 | MTOR (0.60) | MTORPIK3CA | |
| SCHEMBL1830311 | 1.00 | MTOR (0.60) | MTORPIK3CA | |
| SCHEMBL1830033 | 0.89 | MTOR (0.63) | MTORPIK3CA | |
| SCHEMBL1830031 | 0.89 | MTOR (0.63) | MTORPIK3CA | |
| SCHEMBL1835676 | 0.89 | MTOR (0.63) | MTORPIK3CA | |
| SCHEMBL15189893 | 0.86 | MTOR (0.64) | MTORPIK3CA | |
| SCHEMBL1833167 | 0.83 | MTOR (0.68) | MTORPIK3CA | |
| SCHEMBL1831988 | 0.83 | MTOR (0.68) | MTORPIK3CA | |
| SCHEMBL1831987 | 0.83 | MTOR (0.68) | MTORPIK3CA | |
| SCHEMBL1831792 | 0.81 | MTOR (0.67) | MTORPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2318377-B1 | PYRIMIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | GENENTECH INC (US) | 2013-08-21 | — | — | EP | claimed |
| US-8163763-B2 | Pyrimidine compounds, compositions and methods of use | GENENTECH, INC. (US) | 2012-04-24 | — | — | US | claimed |
| EP-2318377-B1 | PYRIMIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | GENENTECH INC (US) | 2013-08-21 | — | — | EP | disclosed |
| EP-2318377-A1 | PYRIMIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | Genentech, Inc. (US) | 2011-05-11 | — | — | EP | disclosed |
| WO-2010014939-A1 | PYRIMIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | GENENTECH, INC. (US) | 2010-02-04 | — | — | WO | disclosed |