Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 8/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 5/20 | 0.39 |
| ▸ | BRD2 | P25440 | 3/20 | 0.38 |
| ▸ | BRD3 | Q15059 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18359511 | 0.88 | FFAR1 (0.39) | FFAR1P2RX7BRD4BRD2BRD3 | |
| SCHEMBL18359497 | 0.83 | BRD4 (0.42) | BRD4BRD2BRD3CYP3A4CYP2C9 | |
| SCHEMBL18359548 | 0.81 | BRD4 (0.55) | BRD4BRD2BRD3CYP3A4CYP2C9 | |
| SCHEMBL18359592 | 0.76 | BRD4 (0.53) | BRD4BRD2BRD3CYP3A4CYP2C9 | |
| SCHEMBL18359510 | 0.75 | BRD4 (0.49) | BRD4BRD2BRD3CYP3A4CYP2C9 | |
| SCHEMBL18359666 | 0.75 | CYP3A4 (0.48) | BRD4BRD2BRD3CYP3A4CYP2C9 | |
| SCHEMBL20547072 | 0.74 | BRD4 (0.53) | BRD4BRD2BRD3CYP3A4CYP2C9 | |
| SCHEMBL18359573 | 0.74 | CYP3A4 (0.41) | FFAR1BRD4BRD2BRD3CYP3A4 | |
| SCHEMBL18359630 | 0.73 | BRD4 (0.47) | FFAR1BRD4BRD2BRD3CYP3A4 | |
| SCHEMBL20547087 | 0.73 | CYP3A4 (0.42) | BRD4BRD2BRD3CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017001733-A1 | BICYCLIC HETEROCYCLE DERIVATIVES AS BROMODOMAIN INHIBITORS | ORION CORPORATION (FI) | 2017-01-05 | — | — | WO | disclosed |