⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15259018 | 1.00 | — | — | |
| SCHEMBL15259051 | 0.91 | — | — | |
| SCHEMBL15289762 | 0.91 | — | — | |
| SCHEMBL12453964 | 0.81 | — | — | |
| SCHEMBL13532542 | 0.78 | — | — | |
| SCHEMBL17131382 | 0.78 | — | — | |
| SCHEMBL17130311 | 0.78 | — | — | |
| SCHEMBL15259022 | 0.77 | — | — | |
| SCHEMBL15259013 | 0.77 | — | — | |
| SCHEMBL13667907 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3210993-A1 | 2'- SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | Gilead Sciences, Inc. (US) | 2017-08-30 | — | — | EP | disclosed |
| EP-2834258-B1 | 2'- SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES INC (US) | 2017-01-04 | — | — | EP | disclosed |