SCHEMBL18359848

SCHEMBL18359848

CC(=O)N[C@H](Cc1ccccc1)C(=O)N[C@H]1CSSC[C@@H](C(=O)N[C@H](CSSc2ccccn2)C(N)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCNC(=O)OC(C)(C)C)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O

nearest known ligand 0.68

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ SSTR2 P30874 15/20 0.68
▸ SSTR4 P31391 10/20 0.58
▸ SSTR5 P35346 10/20 0.58
▸ SSTR3 P32745 4/20 0.58
▸ SSTR1 P30872 2/20 0.56
▸ TP53 P04637 2/20 0.53
▸ MDM2 Q00987 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18359860 1.00 SSTR2 (0.68) SSTR2SSTR4SSTR5SSTR3SSTR1
SCHEMBL18359971 0.97 SSTR2 (0.68) SSTR2SSTR4SSTR5SSTR3SSTR1
SCHEMBL20963116 0.96 SSTR2 (0.66) SSTR2SSTR4SSTR5SSTR3SSTR1
SCHEMBL18359858 0.96 SSTR2 (0.66) SSTR2SSTR4SSTR5SSTR3SSTR1
SCHEMBL18359996 0.96 SSTR2 (0.66) SSTR2SSTR4SSTR5SSTR3SSTR1
SCHEMBL18359970 0.96 SSTR2 (0.66) SSTR2SSTR4SSTR5SSTR3SSTR1
SCHEMBL18359972 0.95 SSTR2 (0.65) SSTR2SSTR4SSTR5SSTR3SSTR1
SCHEMBL18359867 0.93 SSTR2 (0.68) SSTR2SSTR4SSTR5SSTR3SSTR1
SCHEMBL18359862 0.92 SSTR2 (0.62) SSTR2SSTR4SSTR5SSTR3SSTR1
SCHEMBL18359859 0.92 SSTR2 (0.67) SSTR2SSTR4SSTR5SSTR3SSTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190125888-A1 TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF TVA (ABC), LLC 2019-05-02 — — US disclosed
WO-2017003940-A1 TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF TARVEDA THERAPEUTICS, INC. (US) 2017-01-05 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190125888-A1 TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF SSTR4, SSTR5, SSTR1 SSTR2 4/4885SSTR4 1/4885SSTR5 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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