Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | CPT2 | P23786 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 9/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.31 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1840079 | 1.00 | FFAR1 (0.42) | FFAR1CPT2TDP1TSHRTHRB | |
| SCHEMBL27946423 | 0.94 | TSHR (0.47) | FFAR1CPT2TDP1TSHRTHRB | |
| SCHEMBL28111510 | 0.94 | TSHR (0.47) | FFAR1CPT2TDP1TSHRTHRB | |
| SCHEMBL8896801 | 0.94 | TSHR (0.47) | FFAR1CPT2TDP1TSHRTHRB | |
| SCHEMBL4800227 | 0.94 | TSHR (0.47) | FFAR1CPT2TDP1TSHRTHRB | |
| SCHEMBL24268086 | 0.94 | TSHR (0.47) | FFAR1CPT2TDP1TSHRTHRB | |
| Ammonia Solution, Strong SCHEMBL27916022 | 0.91 | TSHR (0.44) | FFAR1CPT2TDP1TSHRTHRB | |
| SCHEMBL21925320 | 0.90 | TSHR (0.41) | FFAR1CPT2TDP1TSHRTHRB | |
| Hydrochloric Acid SCHEMBL27820072 | 0.89 | TSHR (0.42) | FFAR1CPT2TDP1TSHRTHRB | |
| SCHEMBL21549958 | 0.87 | TSHR (0.53) | FFAR1CPT2TDP1TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001755-B1 | CARBOXYLIC ACIDS AND DERIVATIVES THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYNDROME X LTD (IL) | 2011-05-11 | — | — | EP | disclosed |
| CN-101677982-A | Combination therapy, composition and methods for the treatment of cardiovascular disorders | SYNDROMEX LTD | 2010-03-24 | — | — | CN | disclosed |
| US-6303653-B1 | THERAPY OF HEPATOCYTE NUCLEAR FACTOR-4.ALPHA..SUP.1 (HNF-4) MEDIATED DISEASE BY ADMINISTERING CARBOXYLIC ACID OR ITS DERIVATIVE WHICH INHIBITS HNF-4 CONTROLLED TRANSCRIPTION | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2001-10-16 | — | — | US | disclosed |
| EP-1001755-A2 | CARBOXYLIC ACIDS AND DERIVATIVES THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999000116-A2 | CARBOXYLIC ACIDS AND DERIVATIVES THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (US) | 1999-01-07 | — | — | WO | disclosed |