Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 3/20 | 0.38 |
| ▸ | LIPE | Q05469 | 3/20 | 0.38 |
| ▸ | ATF4 | P18848 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18092130 | 0.93 | TSHR (0.55) | TSHRTAAR1TRPV1FAAHLIPE | |
| SCHEMBL983463 | 0.88 | TSHR (0.63) | TSHRFAAHALDH1A1RAB9A | |
| SCHEMBL1840943 | 0.87 | TSHR (0.58) | TSHRFAAHALDH1A1RAB9A | |
| SCHEMBL16942584 | 0.87 | TSHR (0.58) | TSHRALDH1A1RAB9A | |
| Carbamic Acid SCHEMBL29886440 | 0.85 | TSHR (0.59) | TSHRFAAHALDH1A1RAB9A | |
| SCHEMBL19491097 | 0.84 | TSHR (0.71) | TSHRTAAR1FAAHTDP1ALDH1A1 | |
| SCHEMBL1952531 | 0.84 | TSHR (0.55) | TSHRTRPV1TDP1RAB9A | |
| SCHEMBL1952647 | 0.84 | TSHR (0.55) | TSHRTDP1ALDH1A1RAB9A | |
| SCHEMBL18419017 | 0.84 | TSHR (0.57) | TSHRTDP1ALDH1A1RAB9A | |
| SCHEMBL16141999 | 0.83 | TSHR (0.54) | TSHRFAAHTDP1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2322504-A1 | PROCESS FOR THE PREPARATION OF N-SUBSTITUTED CARBAMIC ACID ESTER AND PROCESS FOR THE PREPARATION OF ISOCYANATE USING THE N-SUBSTITUTED CARBAMIC ACID ESTER | Asahi Kasei Chemicals Corporation (JP) | 2011-05-18 | — | — | EP | disclosed |