SCHEMBL1837511

SCHEMBL1837511

CCCN(CCC)c1ccc(O)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESRRG P62508 5/20 0.55
EGFR P00533 2/20 0.44
ERBB2 P04626 1/20 0.44
ESR1 P03372 7/20 0.43
NR1H2 P55055 1/20 0.43
NR1H3 Q13133 1/20 0.43
S1PR1 P21453 1/20 0.42
S1PR3 Q99500 1/20 0.42
ESR2 Q92731 3/20 0.41
CNR2 P34972 1/20 0.41
ALDH1A1 P00352 3/20 0.39
LMNA P02545 3/20 0.39
ADRA2A P08913 3/20 0.39
ADORA3 P0DMS8 3/20 0.39
TACR2 P21452 3/20 0.39
SLC6A2 P23975 3/20 0.39
SLC6A4 P31645 3/20 0.39
SLC6A3 Q01959 3/20 0.39
MAPT P10636 2/20 0.39
TP53 P04637 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24359214 0.94 ESRRG (0.51) ESRRGEGFRERBB2ESR1NR1H2
SCHEMBL6880638 0.92 NR1H2 (0.52) ESRRGEGFRERBB2ESR1NR1H2
SCHEMBL6880660 0.91 ESRRG (0.57) ESRRGESR1NR1H2NR1H3S1PR1
SCHEMBL27980970 0.90 ESRRG (0.56) ESRRGEGFRERBB2ESR1NR1H2
SCHEMBL6881383 0.90 ESRRG (0.49) ESRRGEGFRERBB2ESR1NR1H2
SCHEMBL10486515 0.88 ESRRG (0.48) ESRRGEGFRERBB2ESR1NR1H2
SCHEMBL6881604 0.88 ESR1 (0.48) ESRRGEGFRESR1NR1H2NR1H3
SCHEMBL10486514 0.88 ESRRG (0.48) ESRRGEGFRERBB2ESR1NR1H2
SCHEMBL7150414 0.87 EGFR (0.47) ESRRGEGFRERBB2CNR2ALDH1A1
SCHEMBL24404041 0.87 ESRRG (0.61) ESRRGEGFRERBB2ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0853079-B1 Production of keto acids CIBA SC HOLDING AG (CH) 2002-06-05 EP claimed
US-5925787-A Production of keto acids CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-07-20 US claimed
EP-0853079-A1 Production of keto acids Ciba SC Holding AG (CH) 1998-07-15 EP claimed
EP-3838892-B1 METHOD FOR PRODUCING ISOCYANATE ASAHI CHEMICAL IND (JP) 2022-10-12 EP disclosed
CN-109134336-B Diaryl ether compound, preparation method and application thereof 北京大学深圳研究生院 2021-08-03 CN disclosed
EP-3293173-B1 METHOD FOR PRODUCING ISOCYANATE ASAHI CHEMICAL IND (JP) 2021-07-28 EP disclosed
EP-3838892-A1 METHOD FOR PRODUCING ISOCYANATE Asahi Kasei Kabushiki Kaisha (JP) 2021-06-23 EP disclosed
EP-2980066-B1 METHOD FOR PRODUCING ISOCYANATE ASAHI CHEMICAL IND (JP) 2021-04-21 EP disclosed
CN-107266338-B The manufacturing method of isocyanates 旭化成株式会社 2019-10-11 CN disclosed
CN-109134336-A Two fragrant ether compounds and its preparation method and application 北京大学深圳研究生院 2019-01-04 CN disclosed
EP-3153499-B1 METHOD FOR PRODUCING N-SUBSTITUTED CARBAMIC ACID ESTER ASAHI CHEMICAL IND (JP) 2018-09-19 EP disclosed
WO-2000012318-A1 MONOPHASE SOLID SOLUTIONS COMPRISING A PLURALITY OF COLOUR FORMER COMPOUNDS AND PROCESS FOR THEIR PREPARATION CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-03-09 WO disclosed
US-5985281-A ANTIBODY DIRECTED ENZYME PRODRUG THERAPY (ADEPT) USING A NON-NATURALLY OCCURING MUTANT FORM OF A HOST ENZYME, ESPECIALLY A MUTANT FORM OF RIBONUCLEASE. ZENECA LIMITED (GB) 1999-11-16 US disclosed
US-5925787-A Production of keto acids CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-07-20 US disclosed
US-5869218-A HYDRAZINE DERIVATIVE, PHOSPHONIUM COMPOUND, ASCORBIC ACID DERIVATIVE, AMINOPHENOL DEVELOPER FREE OF A DIHYDROXYBENZENE FUJI PHOTO FILM CO., LTD. (JP) 1999-02-09 US disclosed
EP-0853079-A1 Production of keto acids Ciba SC Holding AG (CH) 1998-07-15 EP disclosed
CN-1171054-A Compound (I) ZENECA LTD (GB) 1998-01-21 CN disclosed
EP-0806964-A1 CHEMICAL COMPOUNDS ZENECA LIMITED (GB) 1997-11-19 EP disclosed
WO-1996020011-A1 CHEMICAL COMPOUNDS ZENECA LIMITED (GB) 1996-07-04 WO disclosed
EP-0511019-A2 Method of producing keto acids MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-10-28 EP disclosed