SCHEMBL18375211 — predicted protein targets

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	KMT2A	Q03164	2/20	0.55

▸	EPHX2	P34913	1/20	0.49

▸	CASP3	P42574	2/20	0.44

▸	CTRB1	P17538	2/20	0.43

▸	MDM4	O15151	1/20	0.42

▸	TP53	P04637	1/20	0.42

▸	SLC17A5	Q9NRA2	1/20	0.42

▸	PTPN1	P18031	1/20	0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29408465	1.00	KMT2A (0.55)	KMT2AEPHX2CASP3CTRB1MDM4
SCHEMBL20369405	1.00	KMT2A (0.55)	KMT2AEPHX2CASP3CTRB1MDM4
SCHEMBL24305580	0.89	KMT2A (0.50)	KMT2AEPHX2CASP3MDM4TP53
SCHEMBL29426426	0.89	KMT2A (0.50)	KMT2AEPHX2CASP3MDM4TP53
SCHEMBL19080574	0.83	KMT2A (0.59)	KMT2AEPHX2CASP3MDM4TP53
SCHEMBL1769671	0.83	MDM4 (0.55)	KMT2AEPHX2CASP3MDM4TP53
SCHEMBL1486272	0.83	MDM4 (0.55)	KMT2AEPHX2CASP3MDM4TP53
SCHEMBL29367928	0.83	MDM4 (0.55)	KMT2AEPHX2CASP3MDM4TP53
SCHEMBL29367649	0.83	MDM4 (0.55)	KMT2AEPHX2CASP3MDM4TP53
SCHEMBL30977663	0.83	MDM4 (0.55)	KMT2AEPHX2CASP3MDM4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2017007695-A1	MU OPIOID RECEPTOR MODULATORS	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US)	2017-01-12	—	—	WO	disclosed