Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 11/20 | 0.81 |
| ▸ | PIK3CA | P42336 | 10/20 | 0.81 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.72 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.72 |
| ▸ | CD38 | P28907 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | BRAF | P15056 | 2/20 | 0.52 |
| ▸ | RAF1 | P04049 | 1/20 | 0.51 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.51 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17047554 | 0.90 | PIK3CG (1.00) | PIK3CGPIK3CAPIK3CDPIK3CBMAPK1 | |
| SCHEMBL17047521 | 0.90 | PIK3CG (1.00) | PIK3CGPIK3CAPIK3CDPIK3CBMAPK1 | |
| SCHEMBL17047493 | 0.89 | PIK3CG (1.00) | PIK3CGPIK3CAPIK3CDPIK3CBCD38 | |
| SCHEMBL17055871 | 0.87 | PIK3CG (0.75) | PIK3CGPIK3CAPIK3CDPIK3CBHTT | |
| SCHEMBL17047550 | 0.86 | PIK3CG (1.00) | PIK3CGPIK3CAPIK3CDPIK3CBCD38 | |
| SCHEMBL17047488 | 0.86 | PIK3CG (1.00) | PIK3CGPIK3CAPIK3CDPIK3CBMAPK1 | |
| SCHEMBL17047463 | 0.86 | PIK3CG (0.77) | PIK3CGPIK3CAPIK3CDPIK3CBMAPK1 | |
| SCHEMBL17047482 | 0.84 | PIK3CG (0.82) | PIK3CGPIK3CAPIK3CDPIK3CBMAPK1 | |
| SCHEMBL17047466 | 0.84 | PIK3CG (1.00) | PIK3CGPIK3CAPIK3CDPIK3CBBRAF | |
| SCHEMBL17047570 | 0.82 | PIK3CG (0.84) | PIK3CGPIK3CAPIK3CDPIK3CBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170015662-A1 | 6-ARYL-4-PHENYLAMINO-QUINAZOLINE ANALOGS AS PHOSPHOINOSITIDE-3-KINASE INHIBITORS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170015662-A1 | 6-ARYL-4-PHENYLAMINO-QUINAZOLINE ANALOGS AS PHOSPHOINOSITIDE-3-KINASE INHIBITORS | PIK3CA, PI4KA, PDPK1 | PIK3CG 5/4885PIK3CA 1/4885PIK3CD 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.