Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 17/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CD4 | P01730 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16738983 | 0.89 | BRD4 (0.42) | BRD4CYP19A1 | |
| SCHEMBL18387202 | 0.86 | BRD4 (0.35) | BRD4CYP19A1 | |
| SCHEMBL16739011 | 0.77 | BRD4 (0.43) | BRD4 | |
| SCHEMBL16739052 | 0.74 | BRD4 (0.43) | BRD4 | |
| SCHEMBL16738925 | 0.73 | BRD4 (0.47) | BRD4 | |
| SCHEMBL16739060 | 0.73 | BRD4 (0.48) | BRD4CYP19A1 | |
| SCHEMBL16738927 | 0.69 | BRD4 (0.47) | BRD4 | |
| SCHEMBL16758591 | 0.69 | BRD4 (0.46) | BRD4 | |
| SCHEMBL16739024 | 0.68 | BRD4 (0.46) | BRD4 | |
| SCHEMBL18387210 | 0.68 | BRD4 (0.35) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170014418-A1 | BICYCLIC HETEROCYCLES AS BET PROTEIN INHIBITORS | INCYTE CORPORATION | 2017-01-19 | — | — | US | disclosed |
| US-20170014418-A1 | BICYCLIC HETEROCYCLES AS BET PROTEIN INHIBITORS | INCYTE CORPORATION | 2017-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170014418-A1 | BICYCLIC HETEROCYCLES AS BET PROTEIN INHIBITORS | BRD1, BRD3, BRD2 | BRD4 4/4885CYP19A1 3799/4885CD4 3958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.