Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CTSC | P53634 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | TNKS | O95271 | 2/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.32 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.32 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.32 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18385879 | 1.00 | NPC1 (0.39) | NPC1RAB9ACTSCCYP3A4ESR2 | |
| SCHEMBL8767041 | 0.95 | CYP3A4 (0.36) | NPC1RAB9ACTSCCYP3A4ESR2 | |
| SCHEMBL8767043 | 0.95 | CYP3A4 (0.36) | NPC1RAB9ACTSCCYP3A4ESR2 | |
| SCHEMBL28574546 | 0.94 | NPC1 (0.42) | NPC1RAB9ACYP3A4ESR2CYP2C9 | |
| SCHEMBL17210747 | 0.94 | NPC1 (0.42) | NPC1RAB9ACYP3A4ESR2CYP2C9 | |
| SCHEMBL18857328 | 0.93 | HSP90AA1 (0.39) | NPC1RAB9ACTSCCYP3A4CYP2C9 | |
| SCHEMBL18458536 | 0.92 | ESR2 (0.47) | NPC1RAB9ACTSCCYP3A4ESR2 | |
| SCHEMBL4438458 | 0.92 | ESR2 (0.46) | NPC1RAB9ACTSCCYP3A4ESR2 | |
| SCHEMBL12056674 | 0.92 | NPC1 (0.34) | NPC1RAB9ACTSCCYP3A4CYP2C9 | |
| SCHEMBL19621368 | 0.92 | KDM1A (0.38) | NPC1RAB9ACTSCCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9994769-B2 | Liquid crystal composition | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO, LTD. (CN) | 2018-06-12 | — | — | US | disclosed |
| US-9994769-B2 | Liquid crystal composition | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO, LTD. (CN) | 2018-06-12 | — | — | US | disclosed |
| US-20170015906-A1 | LIQUID CRYSTAL COMPOSITION | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO, LTD. (CN) | 2017-01-19 | — | — | US | disclosed |
| US-20170015906-A1 | LIQUID CRYSTAL COMPOSITION | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO, LTD. (CN) | 2017-01-19 | — | — | US | disclosed |