Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1833379 | 1.00 | TAAR1 (0.50) | TAAR1CYP2D6 | |
| SCHEMBL1833375 | 1.00 | TAAR1 (0.50) | TAAR1CYP2D6 | |
| SCHEMBL1960870 | 1.00 | TAAR1 (0.50) | TAAR1CYP2D6 | |
| SCHEMBL1960008 | 1.00 | TAAR1 (0.50) | TAAR1CYP2D6 | |
| SCHEMBL1833237 | 0.90 | TAAR1 (0.51) | TAAR1CYP2D6 | |
| SCHEMBL502978 | 0.77 | — | — | |
| SCHEMBL1960474 | 0.77 | — | — | |
| SCHEMBL1833401 | 0.77 | — | — | |
| SCHEMBL1833398 | 0.77 | — | — | |
| SCHEMBL1834492 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2321287-A1 | 4,5-DIHYDRO-OXAZOL-2-YL DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2011-05-18 | — | — | EP | disclosed |
| WO-2010010014-A1 | 4,5-DIHYDRO-OXAZOL-2-YL DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2010-01-28 | — | — | WO | disclosed |