⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL107295 | 1.00 | — | — | |
| SCHEMBL29108602 | 1.00 | MAP3K14 (0.36) | — | |
| SCHEMBL28807141 | 1.00 | MAP3K14 (0.36) | — | |
| SCHEMBL826364 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL31135150 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL31135223 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL31135137 | 0.97 | — | — | |
| SCHEMBL8943397 | 0.84 | — | — | |
| SCHEMBL5818763 | 0.84 | — | — | |
| SCHEMBL9807603 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 285 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112939901-B | Preparation method of alpha-hydroxy-gamma-butyrolactone | 中国科学院福建物质结构研究所 | 2023-05-09 | — | — | CN | claimed |
| CN-112939901-A | Preparation method of alpha-hydroxy-gamma-butyrolactone | 中国科学院福建物质结构研究所 | 2021-06-11 | — | — | CN | claimed |
| US-7632948-B2 | Method of preparing enantiomers of indole-2,3-dione-3-oxime derivatives | NEUROSEARCH A/S (DK) | 2009-12-15 | — | — | US | claimed |
| CN-1296372-C | Process for preparing enantiomers of indole-2, 3-dione-3-oxime derivatives | NEUROSEARCH AS (DK) | 2007-01-24 | — | — | CN | claimed |
| US-20060178391-A1 | Method of preparing enantiomers of indole-2,3-dione-3-oxime derivatives | NEUROSEARCH A/S (DK) | 2006-08-10 | — | — | US | claimed |
| EP-1532146-B1 | A METHOD OF PREPARING ENANTIOMERS OF INDOLE-2,3-DIONE-3-OXIME DERIVATIVES | NEUROSEARCH AS (DK) | 2006-03-01 | — | — | EP | claimed |
| CN-1671704-A | A method of preparing enantiomers of indole-2,3-dione-3-oxime derivatives | NEUROSEARCH AS (DK) | 2005-09-21 | — | — | CN | claimed |
| EP-1532146-A2 | A METHOD OF PREPARING ENANTIOMERS OF INDOLE-2,3-DIONE-3-OXIME DERIVATIVES | NEUROSEARCH A/S (DK) | 2005-05-25 | — | — | EP | claimed |
| WO-2004018466-A2 | A METHOD OF PREPARING ENANTIOMERS OF INDOLE-2,3-DIONE-3-OXIME DERIVATIVES | NEUROSEARCH A/S (DK) | 2004-03-04 | — | — | WO | claimed |
| US-20260083864-A1 | CONTRAST AGENTS FOR USE IN DIAGNOSTIC COMPUTED TOMOGRAPHY IMAGING | BAYER AG (DE) | 2026-03-26 | — | — | US | disclosed |
| EP-4608453-A1 | EXATECAN-DERIVED ADC LINKER-PAYLOADS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | Merck Sharp & Dohme LLC (US) | 2025-09-03 | — | — | EP | disclosed |
| EP-4583926-A1 | CONTRAST AGENTS FOR USE IN DIAGNOSTIC COMPUTED TOMOGRAPHY IMAGING | Bayer Aktiengesellschaft (DE) | 2025-07-16 | — | — | EP | disclosed |
| EP-4581035-A1 | EXATECAN-DERIVED TOPOISOMERASE-1 INHIBITORS PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | Merck Sharp & Dohme LLC (US) | 2025-07-09 | — | — | EP | disclosed |
| EP-4308551-B1 | NEW CONTRAST AGENT FOR USE IN MAGNETIC RESONANCE IMAGING | BAYER AG (DE) | 2025-04-09 | — | — | EP | disclosed |
| EP-0467132-A2 | 4-Substituted-2-hydroxybutanoates and a process for producing them | CHISSO CORPORATION (JP) | 1992-01-22 | — | — | EP | disclosed |
| EP-0439779-A2 | Process for producing optically active hydroxy lactones | CHISSO CORPORATION (JP) | 1991-08-07 | — | — | EP | disclosed |
| US-4652405-A | Synthesis of 1α,25-dihydroxy-24R-fluorocholecalciferol and 1α,25-dihydroxy-24S-fluorocholecalciferol | HOFFMAN-LA ROCHE INC. (US) | 1987-03-24 | — | — | US | disclosed |
| US-4634692-A | OSTEOPOROSIS | HOFFMANN-LA ROCHE INC. (US) | 1987-01-06 | — | — | US | disclosed |
| EP-0073465-B1 | CHOLECALCIFEROL DERIVATIVES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1986-02-05 | — | — | EP | disclosed |
| EP-0073465-A2 | Cholecalciferol derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1983-03-09 | — | — | EP | disclosed |