Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRA | P11474 | 5/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18399457 | 0.95 | ESRRA (0.50) | ESRRAHSP90AA1ALDH1A1GAANR1I2 | |
| SCHEMBL18399459 | 0.89 | ESRRA (0.49) | ESRRAHSP90AA1ALDH1A1GAANR1I2 | |
| SCHEMBL18399488 | 0.81 | HSP90AA1 (0.45) | HSP90AA1ALDH1A1NR1I2LMNACYP2C9 | |
| SCHEMBL18399485 | 0.81 | ESRRA (0.54) | ESRRAALDH1A1GAANR1I2LMNA | |
| SCHEMBL16838066 | 0.81 | AR (0.37) | ESRRALMNAARHSD11B1L3MBTL1 | |
| SCHEMBL25288228 | 0.78 | ESRRA (0.44) | ESRRAHSP90AA1ALDH1A1ARPOLB | |
| SCHEMBL15831658 | 0.78 | AR (0.40) | ESRRALMNAARHSD11B1L3MBTL1 | |
| SCHEMBL18400617 | 0.78 | ESRRA (0.45) | ESRRAALDH1A1LMNAALOX15HTT | |
| SCHEMBL18399484 | 0.77 | HSP90AA1 (0.42) | HSP90AA1ALDH1A1NR1I2LMNACYP2C9 | |
| SCHEMBL15745076 | 0.77 | NR4A1 (0.42) | ESRRAALDH1A1ARHSD11B1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9550711-B2 | Fluorine-containing polymerizable monomer and polymer compound using same | CENTRAL GLASS COMPANY, LIMITED (JP) | 2017-01-24 | — | — | US | disclosed |