SCHEMBL18400656

SCHEMBL18400656

CC(C)(c1ccc(O)cc1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)c(O)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 7/20 0.52
ESR2 Q92731 4/20 0.52
HSD17B10 Q99714 3/20 0.52
CYP3A4 P08684 2/20 0.52
TSHR P16473 2/20 0.52
HPGD P15428 2/20 0.52
AR P10275 1/20 0.52
SLC6A2 P23975 1/20 0.52
SLC6A4 P31645 1/20 0.52
HTR6 P50406 1/20 0.52
ESRRG P62508 1/20 0.52
SLC6A3 Q01959 1/20 0.52
ALDH1A1 P00352 2/20 0.46
ALOX15 P16050 3/20 0.41
MEN1 O00255 1/20 0.41
MAPK1 P28482 1/20 0.41
KMT2A Q03164 1/20 0.41
KCNJ11 Q14654 1/20 0.40
LMNA P02545 1/20 0.38
TYR P14679 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18399466 0.87 ESR1 (0.52) ESR1ESR2HSD17B10CYP3A4TSHR
SCHEMBL18400668 0.87 ESR1 (0.52) ESR1ESR2HSD17B10CYP3A4TSHR
SCHEMBL18400643 0.87 ESR1 (0.52) ESR1ESR2HSD17B10CYP3A4TSHR
SCHEMBL18400662 0.87 ESR1 (0.46) ESR1ESR2HSD17B10CYP3A4TSHR
SCHEMBL18400665 0.82 ESR1 (0.63) ESR1ESR2HSD17B10CYP3A4TSHR
SCHEMBL18400664 0.81 ESR1 (0.50) ESR1ESR2HSD17B10CYP3A4TSHR
SCHEMBL18400646 0.80 ESR1 (0.52) ESR1ESR2HSD17B10CYP3A4TSHR
SCHEMBL2506023 0.79 KCNJ11 (0.47) ESR1ESR2HSD17B10TSHRHPGD
SCHEMBL18399442 0.77 ESR1 (0.52) ESR1ESR2HSD17B10CYP3A4TSHR
SCHEMBL18399461 0.77 ESR1 (0.52) ESR1ESR2HSD17B10CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170088666-A1 Fluorine-Containing Polymerizable Monomer and Polymer Compound Using Same CENTRAL GLASS COMPANY, LIMITED (JP) 2017-03-30 US disclosed
US-9550711-B2 Fluorine-containing polymerizable monomer and polymer compound using same CENTRAL GLASS COMPANY, LIMITED (JP) 2017-01-24 US disclosed