Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.65 |
| ▸ | HTT | P42858 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | MIF | P14174 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CD74 | P04233 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16296741 | 0.91 | TSHR (0.63) | TSHRHTTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL18402538 | 0.90 | TSHR (0.62) | TSHRHTTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL17312335 | 0.87 | TSHR (0.59) | TSHRHTTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL16296797 | 0.82 | TSHR (0.78) | TSHRHTTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL2757835 | 0.81 | MIF (0.71) | TSHRHTTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL16296890 | 0.81 | TSHR (0.80) | TSHRHTTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL17327966 | 0.79 | TSHR (0.80) | TSHRHTTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL17327981 | 0.79 | TSHR (0.51) | TSHRHTTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL17312297 | 0.78 | TSHR (0.63) | TSHRHTTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL16305142 | 0.78 | TSHR (0.48) | TSHRHTTSMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9549988-B2 | Pharmaceutical compounds targeted by MIF affinity-tethered moieties | RJS Biologics (US) | 2017-01-24 | — | — | US | disclosed |