Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18403366 | 0.87 | MAP3K12 (0.58) | MAP3K12 | |
| SCHEMBL18403216 | 0.86 | MAP3K12 (0.60) | MAP3K12 | |
| SCHEMBL19937676 | 0.85 | MAP3K12 (0.59) | MAP3K12 | |
| SCHEMBL18685619 | 0.85 | MAP3K12 (0.61) | MAP3K12 | |
| SCHEMBL18403358 | 0.85 | MAP3K12 (0.61) | MAP3K12 | |
| SCHEMBL19937587 | 0.85 | MAP3K12 (0.60) | MAP3K12 | |
| SCHEMBL18403196 | 0.85 | MAP3K12 (0.60) | MAP3K12ALOX5AP | |
| SCHEMBL18403217 | 0.85 | MAP3K12 (0.60) | MAP3K12ALOX5AP | |
| SCHEMBL18403280 | 0.85 | MAP3K12 (0.64) | MAP3K12 | |
| SCHEMBL18403297 | 0.83 | MAP3K12 (0.61) | MAP3K12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2945938-B1 | 3-SUBSTITUTED PYRAZOLES AND USE AS DLK INHIBITORS | HOFFMANN LA ROCHE (CH) | 2018-03-07 | — | — | EP | disclosed |
| US-9550777-B2 | 3-substituted pyrazoles and use as DLK inhibitors | GENENTECH, INC. (US) | 2017-01-24 | — | — | US | disclosed |