Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K12 | Q12852 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19937929 | 1.00 | MAP3K12 (0.58) | MAP3K12 | |
| SCHEMBL18403299 | 0.98 | MAP3K12 (0.58) | MAP3K12 | |
| SCHEMBL18685601 | 0.88 | MAP3K12 (0.60) | MAP3K12 | |
| SCHEMBL18403367 | 0.88 | MAP3K12 (0.60) | MAP3K12 | |
| SCHEMBL18403292 | 0.87 | MAP3K12 (0.60) | MAP3K12 | |
| SCHEMBL19937877 | 0.87 | MAP3K12 (0.60) | MAP3K12 | |
| SCHEMBL18403196 | 0.85 | MAP3K12 (0.60) | MAP3K12 | |
| SCHEMBL19937999 | 0.85 | MAP3K12 (0.60) | MAP3K12 | |
| SCHEMBL19939288 | 0.85 | MAP3K12 (0.60) | MAP3K12 | |
| SCHEMBL18403217 | 0.85 | MAP3K12 (0.60) | MAP3K12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9550777-B2 | 3-substituted pyrazoles and use as DLK inhibitors | GENENTECH, INC. (US) | 2017-01-24 | — | — | US | disclosed |