Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.33 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.33 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.33 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10269509 | 0.66 | GUCY1B2 (0.65) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL18899199 | 0.66 | GUCY1B2 (0.51) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL18899189 | 0.65 | — | — | |
| SCHEMBL3437542 | 0.63 | GUCY1B2 (0.56) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL15069068 | 0.61 | GUCY1B2 (0.54) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL16202158 | 0.60 | GUCY1B2 (0.55) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL18404986 | 0.60 | GUCY1B2 (0.52) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL18405244 | 0.59 | GUCY1B2 (0.72) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL3437521 | 0.59 | GUCY1B2 (0.53) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL16058247 | 0.59 | GUCY1B2 (0.65) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588465-B1 | SGC STIMULATORS | IRONWOOD PHARMACEUTICALS INC (US) | 2017-01-25 | — | — | EP | disclosed |