Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.35 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.35 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.35 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.35 |
| ▸ | SLC10A1 | Q14973 | 4/20 | 0.34 |
| ▸ | AR | P10275 | 11/20 | 0.33 |
| ▸ | PGR | P06401 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17700898 | 0.88 | GRM4 (0.41) | GRM4ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL17700964 | 0.88 | GRM4 (0.41) | GRM4ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL16257319 | 0.86 | GRM4 (0.41) | GRM4ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL16257389 | 0.86 | GRM4 (0.41) | GRM4ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL16257185 | 0.86 | GRM4 (0.43) | GRM4ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL19825540 | 0.84 | GRM4 (0.40) | GRM4ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL16257204 | 0.84 | GRM4 (0.40) | GRM4ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL16257270 | 0.84 | GRM4 (0.40) | GRM4ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL16257263 | 0.83 | GRM4 (0.44) | GRM4ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL18407949 | 0.82 | GRM4 (0.41) | GRM4ABCC9ABCC8KCNJ11KCNJ8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3121164-A1 | SULPHAMOYLPYRROLAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B | Janssen Sciences Ireland UC (IE) | 2017-01-25 | — | — | EP | disclosed |