Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 14/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL241876 | 1.00 | ADORA2A (0.50) | ADORA2AADORA3ADORA1 | |
| SCHEMBL3010957 | 0.91 | ADORA2A (0.46) | ADORA2AADORA3ADORA1 | |
| SCHEMBL10158798 | 0.91 | ADORA2A (0.46) | ADORA2AADORA3ADORA1 | |
| SCHEMBL1412194 | 0.89 | ADORA2A (0.45) | ADORA2AADORA3ADORA1 | |
| SCHEMBL1414915 | 0.89 | ADORA2A (0.50) | ADORA2AADORA3ADORA1 | |
| SCHEMBL1412218 | 0.88 | ADORA2A (0.51) | ADORA2AADORA3ADORA1 | |
| SCHEMBL10158937 | 0.88 | ADORA2A (0.45) | ADORA2AADORA3ADORA1 | |
| SCHEMBL1412134 | 0.87 | ADORA2A (0.43) | ADORA2AADORA3ADORA1 | |
| SCHEMBL244026 | 0.86 | ADORA2A (0.42) | ADORA2AADORA3ADORA1 | |
| SCHEMBL241166 | 0.85 | ADORA2A (0.55) | ADORA2AADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2322525-A1 | Purine derivatives for use as adenosin A2A receptor agonists | Novartis AG (CH) | 2011-05-18 | — | — | EP | disclosed |