Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 8/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | SNCA | P37840 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 6/20 | 0.55 |
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | GLA | P06280 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL126329 | 0.90 | MAPT (0.67) | APPMAPTSNCANPC1RAB9A | |
| SCHEMBL14423347 | 0.86 | MAPT (0.62) | APPMAPTSNCANPC1RAB9A | |
| SCHEMBL13645849 | 0.85 | MAPT (0.60) | APPMAPTSNCANPC1RAB9A | |
| SCHEMBL13645799 | 0.85 | MAPT (0.63) | APPMAPTSNCANPC1RAB9A | |
| SCHEMBL13645761 | 0.83 | MAPT (0.58) | APPMAPTSNCANPC1RAB9A | |
| SCHEMBL13645798 | 0.83 | MAPT (0.60) | APPMAPTSNCANPC1RAB9A | |
| SCHEMBL1100094 | 0.83 | MAPT (0.60) | APPMAPTSNCANPC1RAB9A | |
| SCHEMBL13645790 | 0.83 | MAPT (0.60) | APPMAPTSNCANPC1RAB9A | |
| SCHEMBL3876366 | 0.82 | MAPT (0.63) | APPMAPTSNCANPC1RAB9A | |
| SCHEMBL13645860 | 0.81 | MAPT (0.59) | APPMAPTSNCANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017013420-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES | POWER OLEDS LIMITED (GB) | 2017-01-26 | — | — | WO | disclosed |