Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | XBP1 | P17861 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tegavivint SCHEMBL14947676 | 0.95 | NPSR1 (0.68) | NPSR1KDM4EMAPTHPGDHTT | |
| Tegavivint SCHEMBL29489537 | 0.95 | NPSR1 (0.68) | NPSR1KDM4EMAPTHPGDHTT | |
| Tegavivint SCHEMBL31694538 | 0.95 | NPSR1 (0.68) | NPSR1KDM4EMAPTHPGDHTT | |
| Tegavivint SCHEMBL13366899 | 0.95 | NPSR1 (0.68) | NPSR1KDM4EMAPTHPGDHTT | |
| SCHEMBL13366831 | 0.95 | NPSR1 (0.68) | NPSR1KDM4EMAPTHPGDHTT | |
| Tegavivint SCHEMBL29372288 | 0.95 | NPSR1 (0.68) | NPSR1KDM4EMAPTHPGDHTT | |
| SCHEMBL20302801 | 0.92 | KDM4E (0.72) | NPSR1KDM4EMAPTHPGDHTT | |
| SCHEMBL18422347 | 0.89 | MAPT (0.58) | NPSR1KDM4EMAPTHPGDHTT | |
| SCHEMBL18422222 | 0.89 | MAPT (0.58) | NPSR1KDM4EMAPTHPGDHTT | |
| SCHEMBL61341 | 0.87 | NPSR1 (0.59) | NPSR1KDM4EMAPTHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3328819-A1 | ANTHRACENE-9, 10-DIONE DIOXIME COMPOUNDS PRODRUGS AND THEIR USES | Beta Cat Pharmaceuticals, Inc. (US) | 2018-06-06 | — | — | EP | disclosed |
| WO-2017019875-A1 | ANTHRACENE-9, 10-DIONE DIOXIME COMPOUNDS PRODRUGS AND THEIR USES | BETA CAT PHARMACEUTICALS, INC. (US) | 2017-02-02 | — | — | WO | disclosed |