SCHEMBL18429347

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL24896933	0.94	SYK (0.46)	SYKIDO1MEN1KMT2AMAPT
	SCHEMBL3628803	0.93	SYK (0.51)	SYKIDO1MEN1KMT2AMAPT
	SCHEMBL8047038	0.93	SYK (0.51)	SYKIDO1MEN1KMT2AMAPT
	SCHEMBL25460174	0.93	SYK (0.47)	SYKIDO1MEN1KMT2AMAPT
	SCHEMBL18429584	0.92	SYK (0.50)	SYKIDO1MEN1KMT2AMAPT
	SCHEMBL3628805	0.91	HTT (0.50)	SYKIDO1MEN1KMT2AMAPT
	SCHEMBL7156418	0.90	SMN1; SMN2 (0.52)	SYKIDO1MAPTHTTSMN1; SMN2
	SCHEMBL25463464	0.88	SYK (0.48)	SYKIDO1MEN1KMT2AMAPT
	SCHEMBL6840857	0.88	SMN1; SMN2 (0.52)	SYKIDO1MAPTHTTSMN1; SMN2
	SCHEMBL24896931	0.87	SYK (0.49)	SYKIDO1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.