Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 10/20 | 0.75 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.75 |
| ▸ | IL6 | P05231 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12175813 | 0.90 | TLR7 (0.78) | TLR7NUDT1IL6 | |
| SCHEMBL29997135 | 0.90 | TLR7 (0.82) | TLR7NUDT1IL6 | |
| SCHEMBL43878 | 0.90 | TLR7 (0.82) | TLR7NUDT1IL6 | |
| SCHEMBL822996 | 0.89 | TLR7 (0.72) | TLR7NUDT1IL6 | |
| SCHEMBL19369897 | 0.89 | TLR7 (0.75) | TLR7NUDT1IL6 | |
| SCHEMBL18429924 | 0.88 | TLR7 (0.74) | TLR7NUDT1IL6 | |
| SCHEMBL20553091 | 0.86 | TLR7 (0.71) | TLR7NUDT1 | |
| SCHEMBL4124603 | 0.86 | TLR7 (0.84) | TLR7NUDT1IL6 | |
| SCHEMBL1641626 | 0.86 | TLR7 (1.00) | TLR7NUDT1IL6 | |
| SCHEMBL29381054 | 0.86 | TLR7 (1.00) | TLR7NUDT1IL6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9556167-B2 | TLR-agonist-conjugated antibody recruiting molecules (TLR-ARMs) | YALE UNIVERSITY (US) | 2017-01-31 | — | — | US | disclosed |