Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1844259 | 0.99 | MAPK1 (0.45) | MAPK1PIK3CAMAPK8MAPK9MAPK10 | |
| Lithium SCHEMBL1844267 | 0.99 | MAPK1 (0.45) | MAPK1PIK3CAMAPK8MAPK9MAPK10 | |
| SCHEMBL1843890 | 0.92 | ABL1 (0.45) | MAPK1PIK3CAMAPK8MAPK9MAPK10 | |
| Lithium Ion SCHEMBL1844263 | 0.91 | NPC1 (0.41) | MAPK1PIK3CAMAPK8MAPK9MAPK10 | |
| SCHEMBL1842971 | 0.91 | ABL1 (0.43) | ABL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1842937 | 0.91 | ABL1 (0.44) | MAPK1PIK3CAMAPK8MAPK9MAPK10 | |
| Lithium SCHEMBL1842944 | 0.91 | ABL1 (0.44) | MAPK1PIK3CAMAPK8MAPK9MAPK10 | |
| Lithium SCHEMBL1842524 | 0.90 | MAPK1 (0.40) | MAPK1PIK3CAMAPK8MAPK9MAPK10 | |
| SCHEMBL1842521 | 0.90 | MAPK1 (0.40) | MAPK1PIK3CAMAPK8MAPK9MAPK10 | |
| SCHEMBL1843004 | 0.88 | MAPK1 (0.43) | MAPK1PIK3CAMAPK8MAPK9MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2321309-A1 | BENZOTHIAZOLES AND AZA-ANALOGUES THEREOF USE AS ANTIBACTERIAL AGENTS | Ranbaxy Laboratories Limited (IN) | 2011-05-18 | — | — | EP | claimed |
| WO-2009156966-A1 | BENZOTHIAZOLES AND AZA-ANALOGUES THEREOF USE AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2009-12-30 | — | — | WO | claimed |