⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Morpholine SCHEMBL28529603 | 1.00 | — | — | |
| Morpholine SCHEMBL18577399 | 1.00 | — | — | |
| SCHEMBL6049109 | 1.00 | MEN1 (0.92) | — | |
| Morpholine SCHEMBL922866 | 1.00 | — | — | |
| Morpholine SCHEMBL986 | 1.00 | — | — | |
| Morpholine SCHEMBL7996463 | 1.00 | MEN1 (0.92) | — | |
| Morpholine SCHEMBL3233209 | 1.00 | MEN1 (0.92) | — | |
| SCHEMBL244992 | 1.00 | MEN1 (0.92) | — | |
| SCHEMBL22491036 | 1.00 | MEN1 (0.92) | — | |
| Morpholine SCHEMBL27542862 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 6617 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410577-B1 | — | — | None | — | — | US | claimed |
| WO-2024138486-A1 | TETRACYCLIC DERIVATIVES AS KRAS INHIBITORS | NIKANG THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | claimed |
| CN-118265699-A | Asymmetric biphenyl derivative and preparation method and medical application thereof | 西安新通药物研究股份有限公司 | 2024-06-28 | — | — | CN | claimed |
| CN-118221579-A | PRMT5 inhibitors | 北京望实智慧科技有限公司 | 2024-06-21 | — | — | CN | claimed |
| EP-4370506-A1 | PYRAZINE COMPOUNDS AS INHIBITORS OF FLT3 | Biomea Fusion, Inc. (US) | 2024-05-22 | — | — | EP | claimed |
| EP-4370132-A2 | MULTIPLEXING TARGETING LIGANDS THROUGH CLICK CHEMISTRY AT THE ANOMERIC SITE OF SUGARS | Alnylam Pharmaceuticals, Inc. (US) | 2024-05-22 | — | — | EP | claimed |
| EP-3852766-B1 | COMBINATION THERAPY FOR TREATING BLOOD CANCER | SIGNALCHEM LIFESCIENCES CORP (CA) | 2024-05-08 | — | — | EP | claimed |
| CN-117982672-A | Anti-Nectin-4 antibody drug conjugate and application | 百奥泰生物制药股份有限公司 | 2024-05-07 | — | — | CN | claimed |
| WO-2024088036-A1 | ASYMMETRIC BIPHENYL DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 西安新通药物研究股份有限公司 | 2024-05-02 | — | — | WO | claimed |
| WO-2024078387-A1 | SUBSTITUTED 3-FLUOROBENZENEPROPANOATE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITIONS, AND USES | 天津谷堆生物医药科技有限公司 | 2024-04-18 | — | — | WO | claimed |
| EP-0110298-A1 | Acridanone derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-06-13 | — | — | EP | claimed |
| EP-0003560-B1 | IMIDAZOLE DERIVATIVES AND SALTS THEREOF, THEIR SYNTHESIS, AND PHARMACEUTICAL FORMULATIONS | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-05-02 | — | — | EP | claimed |
| EP-0107350-A1 | Sulfon amides | Beecham Wuelfing GmbH & Co KG (DE) | 1984-05-02 | — | — | EP | claimed |
| EP-0098951-A2 | Aminobenzamide derivatives and preparation thereof | STERLING DRUG INC. (US) | 1984-01-25 | — | — | EP | claimed |
| US-4416895-A | ANTICOAGULANTS, ANTISHOCK AGENTS | BURROUGHS WELLCOME CO. (US) | 1983-11-22 | — | — | US | claimed |
| EP-0065488-A1 | Process for the preparation of 4-thio-azetidinone compounds | CIBA-GEIGY AG (CH) | 1982-11-24 | — | — | EP | claimed |
| EP-0006722-A1 | Derivatives of (4-(piperazin-1-yl-phenyloxymethyl)-1.3-dioxolan-2-ylmethyl)-1H-imidazoles and -1H-1.2.4-triazoles, their preparation and use as fungicides and bactericides | JANSSEN PHARMACEUTICA N.V. (BE) | 1980-01-09 | — | — | EP | claimed |
| EP-0003560-A2 | Imidazole derivatives and salts thereof, their synthesis, and pharmaceutical formulations | THE WELLCOME FOUNDATION LIMITED (GB) | 1979-08-22 | — | — | EP | claimed |
| US-4160766-A | ANTI-AGGRESSIVES AND ANTIDEPRESSANTS | SANDOZ LTD. (CH) | 1979-07-10 | — | — | US | claimed |
| US-4130710-A | POLYOLEFIN STABILIZERS | CIBA-GEIGY CORPORATION (US) | 1978-12-19 | — | — | US | claimed |